The star studded event again returned to North Greenwich fronted by Dermot O’Leary who opened the celebration dedicated to the famous faces of the small screen.
The BBC One chat show host was again battling against the Geordie duo in the category of Best Entertainment Programme, where The Graham Norton Show was up against the duo’s I’m A Celebrity and Saturday Night Takeaway shows.
But it was the jungle reality TV extravaganza that secured the top accolade, meaning Ant and Dec collected the trophy for the 15th year on the trot.
Graham said on the red carpet: “It’s not annoying - it would be if it was someone useless - but Ant and Dec are brilliant, so you can’t complain if you don’t win an award.”
He added he had his eye on Brad Pitt and Angelina Jolie as his next guests.
Meanwhile Rylan Clark-Neal, who was also up against the pair in the TV presenter section and said: “Them boys deserve 15 on the trot - if I was to win, I think I would die.
“I won’t shake their hand I’ll kiss them on the lips - whether they like it or not!”
But the eastern side of the capital fared better in the Serial Drama award.
Soap EastEnders came out top over long-time rivals Coronation Street and fans of the drama in Albert Square are set for more excitement as the Mitchell family are reunited.
New arrival to the cast Tilly Keeper has taken on the role of Phil Mitchell (Steve McFadden’) daughter Louise.
She said on the red carpet: “The fans love sassy Louise, I love sassy Louise. The fans are lovely and everyone’s saying that, they have really taken to her.
“Working with Steve you never think it will happen but he’s so professional. My first day I couldn’t have asked for a better day. It’s really exciting to have the Mitchell’s back together.”
The drama, which will soon see a huge storyline for the Mitchell family centred on Phil’s alcohol addiction, also has the support of 2015 Bake-Off winner Nadiya Hussain.
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She looked chic in an all-black outfit on the red carpet and told The Wharf as a keen viewer of the NTAs, she “always” backed EastEnders.
She took to the stage as the BBC cook show scooped the accolade for Best Challenge show in what was the first of the evening, before guests tucked into her huge four-tier cake at the afterparty.
Meanwhile, she revealed her upcoming plans.
“It’s been exciting - my feet haven’t touched the ground,” she said. “I’ve got a cookbook coming out in June. I’ve always wanted to do a kids cookbook and I couldn’t miss an opportunity to do one.
“It’s my version of old fairytales and I’ve taken them and changed them round completely.”
Bake-Off legend Mary Berry added: “It’s very exciting - it’s got better than ever, and it’s got Britain baking. It’s a great family show. Nadiya won my heart as well.”
Other winners at the event, which celebrated its 21st anniversary, included Billy Connolly for the Special Recognition Award presented by Dustin Hoffman, Downton Abbey and Doctor Foster, This Morning and Strictly Come Dancing.
Poldark hunk Aidan Turner accepted the new Impact gong which marked the biggest TV moment of the year.