Among the acts are alternative rock band Headlong, pop blues trio Jamie Crawford, Under The Sun and Morning Lane, along with DJ Saytek Live.
Head of fundraising Stephen Armstrong said: “We’re especially pleased that Saytek is supporting us as he is a great role model for those suffering long-term recovery from addictions.
"Having been on drugs since early childhood due to a failed diagnosis of autism, Saytek today is happy, healthy and proof that with the right support, people in recovery can become happy parents, successful musicians and help others to make that same change.”
The night is being organised by volunteers Martina Danielova and SOLU.
April 9, 7pm, £5, 93 Feet East, Brick Lane, Shoreditch, sct.org.uk .