A man and a teenager have died after their car crashed into a van near Canary Wharf.
The car driver, a 23-year-old man, died instantly and an 18-year-old woman in the back of the car was pronounced dead at the scene.
A 23-year-old man, sitting in the front of the car, was taken to hospital with a broken arm.
The driver of the van was not injured.
The three were travelling along Marsh Wall in a black BMW when it crashed at the junction of Manchester Road at about 5.15am on Friday, January 22.
Police and London’s Air Ambulance from Whitechapel were called to the scene, along with the Fire Brigade and Ambulance Service.
Isle of Dogs resident Paul Wilks said he could only see the BMW when he drove past at 8.15am.
He said: “I was driving from the south of the island up Manchester Road and when I got to the blue bridge where the roundabout is you could only drive straight on.
“Police had cordoned off both of those turn offs and there were about four or five police cars in the area and police directing traffic.
“The traffic was almost all the way back to the McDonalds roundabout.
“Driving past I could quickly see the crash was on Marsh Wall, about 10-15m from the roundabout.
“There was a black BMW smashed up on the traffic island and I could see one of those blue tents by it, which made me think there must have been a fatality.
“Yesterday morning when I drove past there was a wrecked car 100m north of that, just abandoned – young people use the area as a race track all the time.”
A London Ambulance spokesman said: “We were called at 5.19am on Friday, January 22, to reports of a road traffic collision at Marsh Wall in E14.
“We sent a number of resources to the scene including the hazardous area response team and a medical team from London’s Air Ambulance by car to the scene.
“Sadly, despite extensive efforts, two patients were pronounced dead at the scene by the doctor from London’s Air Ambulance.
“We also treated a man reported to be in his 20s for an arm injury.
“He was taken as a priority to hospital escorted by the doctor from London’s Air Ambulance.”
Two fire engines and a fire rescue unit from Millwall, Poplar and Bethnal Green fire stations also attended the crash.