Commuters heading to Canary Wharf on the MBNA Thames Clippers will be able to use pay as you go Oyster cards to save themselves money.
From mid-September passengers can touch their card in as they step on deck, then out when they disembark.
This means there will be no need to buy a ticket beforehand, although cards must be in credit.
The catamaran operator has also divided up its routes into zones – East, Central and West – to simplify its pricing structure and offer travellers savings.
For Docklands, East covers all piers between Canary Wharf and Royal Arsenal Woolwich (inclusive) meaning passengers travelling within its confines using Oyster and the firm’s app will save cash.
In this East Zone the headline fare will be £4.20 for single tickets bought at piers, dropping to £3.90 for Oyster and app users.
Previously the headline single fare on the all-stopping RB1 service that covers that journey was £7.15.
The Oyster system will automatically calculate the cheapest fare based on the journey taken.
Contactless cards are not yet supported on the network, although it is hoped this technology will be introduced by summer 2016
The changes come as the operator plans to launch 150-seater vessels this summer.