The sell-out event is in its third year and will be hosted by former EastEnders actresses Brooke Kinsella and Louisa Lytton on Thursday, November 12.
Meanwhile, Brandon Block will be entertaining sleepers with a guest DJ set from 7pm until 7am.
Other entertainment on the night includes a bed-time story by a surprise guest, and a special performance by a young person helped by Centrepoint.
Head of events at Centrepoint Richard Utting said: “While Sleep Out will be celebrating 10 years this year, West India Quay has been a part of it for just three, so it’s fantastic to have it sold out. We’re grateful to our corporate partners for their continuing support.
“Not only does the event do a great job raising a huge amount of money for a fantastic cause, but it also enables individuals to experience just a small taste of what too many young people still go through every night.”
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