Previews: Man Utd v West Ham, Bolton v Charlton, Millwall v Middlesbrough
Manchester United v West Ham
Kick off: Saturday, 3pm
Odds: West Ham: 9/1; Man Utd: 2/5; Draw: 17/4
History of meetings: West Ham won - 42; Man Utd won - 58; Draw - 26
Wednesday night's win in the Capital Cup against Spurs has given West Ham a much needed boost.
Manager Sam Allardyce now wants to take that into the league.
"It's a relief," he told BBC. "For me, the challenge is to get the players to kick on from this."
One player he especially wants to "kick on" is Modibo Maiga, whose winner against Spurs was his first West Ham goal.
James Tomkins is set to feature in the squad after injury.
Meanwhile, Manchester United's Wayne Rooney is struggling with a groin injury.
Bolton v Charlton
Kick off: Saturday, 3pm
Odds: Charlton: 3/1; Bolton 20/19; Draw 5/2
History of meetings: Charlton won - 27; Bolton won - 42; Draw - 14
Charlton's Johnnie Jackson serves the second game of his suspension on Saturday against Bolton. Full-back Chris Solly came through the 5-2 reserve win against Cardiff unscathed and could return for the trip to Bolton.
Ben Hamer and Leon Cort are both out injured, Marvin Sordell isn't allowed to play against his parent club.
Joe Pigott and Tobi Sho Silva scored two goals each in that Cardiff reserve match so could very well feature in Lancashire.
Meanwhile, manager Chris Powell is demanding a turn around in fortunes from his side.
"There is no way in the world this Charlton Athletic squad doesn't have at least six or seven teams that should be below us," he told BBC.
"We are where we are and I can say that all day long. We have to come out the other side with points and moving this great football club forward and up the table."
Millwall v Middlesbrough
Kick off: Saturday, 5.30pm
Odds: Millwall: 9/5; Middlesbrough 17/10; Draw 12/5
History of meetings: Millwall won - 17; Middlesbrough won - 17; Draw - 10
Martyn Waghorn returned to Leicester after his Millwall loan spell. Scott McDonald is likely to replace him for the late kick-off against Middlesbrough.
Paul Robinson and Alan Dunne are both slight doubts at the back. Justin Hoyte will not play against his parent club.
Tickets for Saturday's match, which is televised, cost just £5.
Meanwhile, manager Steve Lomas told Teamtalk.com this week he will have to work clever in the January transfer window.
"It's tough," he said. "English football now, it's not like it was a few years ago when there was massive amounts of money about. We have to wheel and deal and we'll look at doing that in January again."