Westferry walkway to close until late 2013
The Riverside South pathway, which was reopened last year after a residents' campaign, shut again from Monday for 18 months.
Canary Wharf Group, which is working on the site on behalf of its owner JP Morgan, said the closure was necessary to accommodate work to strengthen the river wall.
It follows the temporary reopening of the walkway alongside the Riverside South construction site since last March.
CWG said a diversion will be placed for pedestrians during closure taking them along Westferry Road.
Spokesman Howard Dawber said: "We would like to apologise for the inconvenience caused by the diversion while these necessary works take place.
"We are pleased to have kept the walkway open for over a year. Now it is closing again we will endeavour to complete works as soon as possible.
"When complete, we think people will be pleased with the improvements to the area, which will provide riverside pedestrian access and green space for local people to enjoy for many generations to come."
Prof Ed Berman, who led the campaign to reopen the site last year, is meeting with CWG to discuss the plans.
He said the community needed the link to be kept open and criticised the latest closure.
"Eighteen months is an extraordinary amount of time to reinforce a riverbank," he said.
JP Morgan bought the Riverside South site from CWG in 2008.
CWG closed the walkway due to safety fears but decided it could reopen after carrying out remedial work in the area.